QKI wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human QKI wild-type allele is located in the vicinity of 6q26 and is approximately 165 kb in length. This allele, which encodes protein quaking, plays a role in mRNA biosynthesis, mRNA splicing, mRNA stabilization, oligodendrocyte differentiation and myelination. A fusion of this gene and the NTRK2 gene may be associated with non-cerebellar pilocytic astrocytoma.

**Synonyms:** - HKQ - Hqk - QK - QK1 - QK3 - QKI, KH Domain Containing, RNA Binding wt Allele - Quaking Homolog, KH Domain RNA Binding (Mouse) Gene - Quaking, Mouse, Homolog of Gene - hqkI