WASHC5 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human WASHC5 wild-type allele is located in the vicinity of 8q24.13 and is approximately 68 kb in length. This allele, which encodes WASH complex subunit strumpellin protein, plays a role in the induction of actin polymerization. Mutations in this gene are associated with autosomal dominant spastic paraplegia 8.

**Synonyms:** - KIAA0196 - RTSC - RTSC1 - SPG8 - Spastic Paraplegia 8 (Autosomal Dominant) Gene - WASH Complex Subunit 5 wt Allele