LORICRIN wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human LORICRIN wild-type allele is located in the vicinity of 1q21.3 and is approximately 2 kb in length. This allele, which encodes loricrin protein, is involved in the cell envelope structure of mature keratinocytes. Mutations in this gene are associated with progressive symmetric erythrokeratoderma and Vohwinkel syndrome with ichthyosis.

**Synonyms:** - LOR - LOR wt Allele - LRN - Loricrin Cornified Envelope Precursor Protein wt Allele - Loricrin Gene