KRT10 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human KRT10 wild-type allele is located in the vicinity of 17q21 and is approximately 4 kb in length. This allele, which encodes keratin, type I cytoskeletal 10 protein, is involved in the intermediate filament structure of terminally differentiated epidermal cells. Mutations in this gene are associated with epidermolytic hyperkeratosis, ichthyosis with confetti, and cyclic ichthyosis with epidermolytic hyperkeratosis.

**Synonyms:** - BCIE - BIE - CK-10 - CK10 - EHK - Epidermolytic Hyperkeratosis Gene - K10 - KPP - Keratin 10 wt Allele