MFN2 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human MFN2 wild-type allele is located in the vicinity of 1p36.22 and is approximately 33 kb in length. This allele, which encodes mitofusin-2 protein, plays a role in both GTP hydrolysis and mitochondrial fusion. Mutation of the gene is associated with Charcot-Marie-Tooth disease types 2A2 and 6.

**Synonyms:** - CMT2A - CMT2A2 - CPRP1 - HSG - Hyperplasia Suppressor Gene - KIAA0214 - MARF - Mitofusin 2 wt Allele