SLC47A1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human SLC47A1 wild-type allele is located in the vicinity of 17p11.2 and is approximately 84 kb in length. This allele, which encodes multidrug and toxin extrusion protein 1, is involved in solute transport of cationic drugs across brush border membranes. Mutations in this gene are associated with Smith-Magenis syndrome and lactic acidosis.

**Synonyms:** - FLJ10847 - MATE-1 - MATE1 - Solute Carrier Family 47 (Multidrug and Toxin Extrusion), Member 1 wt Allele - hMATE-1