ABCG1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human ABCG1 wild-type allele is located in the vicinity of 21q22.3 and is approximately 98 kb in length. This allele, which encodes ATP-binding cassette sub-family G member 1 protein, plays a role in lipid homeostasis. Aberrant expression of the gene in macrophages is associated with Tangier disease.

**Synonyms:** - ABC8 - ATP-Binding Cassette, Sub-Family G (WHITE), Member 1 wt Allele - ATP-Binding Cassette, Subfamily G, Member 1 Gene - Homolog of Drosophila White Gene - WHITE1 - WHT1 - White Protein Homolog (ATP-Binding Cassette Transporter 8) Gene - White, Drosophila, Homolog of Gene