ERN1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human ERN1 wild-type allele is located in the vicinity of 17q24.2 and is approximately 88 kb in length. This allele, which encodes serine/threonine-protein kinase/endoribonuclease IRE1, plays a role in the unfolded protein response.

**Synonyms:** - ER To Nucleus Signalling 1 Gene - Endoplasmic Reticulum To Nucleus Signaling 1 wt Allele - IRE1 - IRE1P - IRE1a - Inositol-Requiring 1 Gene - Inositol-Requiring Enzyme 1, S. cerevisiae, Homolog of Gene - hIRE1p