SERPIND1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human SERPIND1 wild-type allele is located in the vicinity of 22q11.21 and is approximately 14 kb in length. This allele, which encodes heparin cofactor 2 protein, is involved in heparin-dependent inhibition of thrombin. Mutation of the gene is associated with thrombophilia due to heparin cofactor 2 deficiency.

**Synonyms:** - D22S673 - HC2 - HCF2 - HCII - HLS2 - LS2 - Serine (Or Cysteine) Proteinase Inhibitor, Clade D (Heparin Cofactor), Member 1 Gene - Serpin Peptidase Inhibitor, Clade D (Heparin Cofactor), Member 1 wt Allele - THPH10