Hypoxia Inducible Factor Family

**Semantic type:** Amino Acid, Peptide, or Protein

**Definition:** A family of basic helix-loop-helix heterodimeric transcription factors that activate gene expression when oxygen levels decrease in the cellular environment. Each HIF complex is comprised of an alpha subunit and beta subunit, which are encoded by separate genes.

**Synonyms:** - HIF - HIF Factor - HIF Family - Hypoxia Inducible Factor - Hypoxia-Inducible Factor - Hypoxia-Inducible Factor Family