Autologous CD8+ Melanoma Specific T Cells

**Semantic type:** Cell|Pharmacologic Substance

**Definition:** Autologous CD8 T-lymphocytes against melanoma-associated antigens, with potential immunomodulating and antineoplastic activities. Following leukapheresis and the ex vivo expansion of cytotoxic T-lymphocytes, the autologous CD8+ melanoma specific T-cells are re-introduced into the melanoma patient. These cytotoxic T-cells recognize and kill the patient's own melanoma cells.

**Synonyms:** - Autologous Melanoma Specific Cytotoxic T Lymphocytes