Bacterial Artificial Chromosome Array-based Comparative Genomic Hybridization

**Semantic type:** Molecular Biology Research Technique

**Definition:** A molecular cytogenetic method combining chromosomal comparative genomic hybridization technique and microarray to detect chromosomal aberrations and changes in DNA copy numbers, using bacterial artificial chromosome clones containing target DNA fragments for hybridization. This method is especially sensitive in detecting single copy changes in the genome.

**Synonyms:** - BAC ACGH - BAC Array-based CGH - Bacterial Artificial Chromosome Array-based CGH