SOS1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human SOS1 wild-type allele is located in the vicinity of 2p21 and is approximately 143 kb in length. This allele, which encodes son of sevenless homolog 1 protein, plays a role in both signaling and guanine nucleotide exchange. Mutation of the gene is associated with both gingival fibromatosis type 1 and Noonan syndrome type 4.

**Synonyms:** - GF1 - GGF1 - GINGF - Gingival Fibromatosis, Hereditary, 1 Gene - HGF - NS4 - SOS Ras/Rho Guanine Nucleotide Exchange Factor 1 wt Allele - Son of Sevenless Homolog 1 (Drosophila) Gene - Son of Sevenless Homolog 1 Gene - Son of Sevenless, Drosophila, Homolog 1 Gene