PDGFR-AA

**Semantic type:** Amino Acid, Peptide, or Protein|Enzyme

**Definition:** A homodimeric protein complex comprised of 2 platelet-derived growth factor receptor alpha proteins. Formation of this complex is dependent on the binding of a disulfide-linked homodimer of platelet-derived growth factor alpha. The formation of the receptor dimer activates its intrinsic tyrosine-protein kinase activity and initiates signal transduction pathways.

**Synonyms:** - Platelet-Derived Growth Factor Receptor Alpha Homodimeric Complex