Autologous Cytomegalovirus-specific Cytotoxic T-lymphocytes

**Semantic type:** Cell|Pharmacologic Substance

**Definition:** A population of autologous cytotoxic-T lymphocytes (CTLs) specifically reactive to the herpes virus cytomegalovirus (CMV) with potential immunomodulating and antiviral activities. Upon administration with the autologous CMV-specific CTLs, these CTLs lyse CMV-infected cells, thereby preventing or decreasing the occurrence of CMV viral disease, or reducing the amount of antiviral drug therapy needed to eradicate CMV.

**Synonyms:** - Autologous CMV-specific CTLs