APOBEC3A wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human APOBEC3A wild-type allele is located within 22q13.1-q13.2 and is approximately 10 kb in length. This allele, which encodes DNA dC->dU-editing enzyme APOBEC-3A protein, plays a role in the modulation of viral DNA modification. A deletion that fuses this gene and the 3' end of the APOBEC3B gene may be associated with increased susceptibility to neoplastic disease.

**Synonyms:** - A3A - ARP3 - Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3A wt Allele - PHRBN - bK150C2.1