DNA2 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human DNA2 wild-type allele is located within 10q21.3-q22.1 and is approximately 58 kb in length. This allele, which encodes DNA replication ATP-dependent helicase/nuclease DNA2 protein, plays a role in DNA replication and repair. Mutation of the gene is associated with autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions type 6 and may be associated with Seckel Syndrome 8.

**Synonyms:** - DNA Replication Helicase 2 Homolog (Yeast) Gene - DNA Replication Helicase 2, Yeast, Homolog of Gene - DNA Replication Helicase/Nuclease 2 wt Allele - DNA2 DNA Replication Helicase 2-Like (Yeast) Gene - DNA2-Like Gene - DNA2L - PEOA6 - RP11-9E13.1 - SCKL8 - hDNA2