Amyloid

**Semantic type:** Amino Acid, Peptide, or Protein

**Definition:** An insoluble, fibrous aggregate of misfolded proteins or protein fragments. These fibrillar structures usually exhibit a cross-beta-sheet conformation. Deposition of amyloid aggregates is associated with a number of pathologies including amyloidosis and several neurodegenerative disorders.

**Synonyms:** - Amyloid Protein