IDH1 NP_005887.2:p.R132X

**Semantic type:** Cell or Molecular Dysfunction

**Definition:** A change in the amino acid residue at position 132 in the isocitrate dehydrogenase [NADP] cytoplasmic protein where arginine has been replaced by another amino acid. Mutations at this position occur frequently in high-grade gliomas but not in other solid tumors.

**Synonyms:** - Cytosolic NADP-Isocitrate Dehydrogenase Protein Arg132Xxx - Cytosolic NADP-Isocitrate Dehydrogenase Protein R132X - IDH1 Arg132Xxx - IDH1 NP_005887.2:p.Arg132Xxx - IDH1 R132 - IDH1 R132 - IDH1 R132 Mutation - IDH1 R132X - IDH1 R132X Mutation - IDH1 p.Arg132Xxx - IDH1 p.R132 - IDH1 p.R132X - IDH1-R132 Mutation - Isocitrate Dehydrogenase [NADP] Cytoplasmic Arg132Xxx - Isocitrate Dehydrogenase [NADP] Cytoplasmic R132X - NP_005887.2:p.Arg132Xxx - NP_005887.2:p.R132X