IDH2 NP_002159.2:p.R172X

**Semantic type:** Cell or Molecular Dysfunction

**Definition:** A change in the amino acid residue at position 172 in the isocitrate dehydrogenase [NADP], mitochondrial protein where arginine has been replaced by another amino acid. Mutations at this position are found in patients with acute myeloid leukemia following myelodysplastic syndromes and is associated with shorter overall survival.

**Synonyms:** - IDH2 Arg172Xxx - IDH2 R172 - IDH2 R172 - IDH2 R172 Mutation - IDH2 R172X - IDH2 p.Arg172Xxx - IDH2 p.R172 - IDH2(R172) - Isocitrate Dehydrogenase 2 (NADP+) Mitochondrial Arg172Xxx - Isocitrate Dehydrogenase 2 (NADP+) Mitochondrial R172X - Isocitrate Dehydrogenase [NADP+], Mitochondrial R172X - Isocitrate Dehydrogenase [NADP], Mitochondrial Arg172Xxx - NP_002159.2:p.Arg172Xxx - NP_002159.2:p.R172X