NECTIN1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human NECTIN1 wild-type allele is located in the vicinity of 11q23.3 and is approximately 106 kb in length. This allele, which encodes nectin-1 protein, is involved in both viral entry and the promotion of cell-cell adhesion. Mutation of the gene is associated with both cleft lip/palate-ectodermal dysplasia syndrome and orofacial cleft 7.

**Synonyms:** - CD111 - CLPED1 - ED4 - Ectodermal Dysplasia 4 (Margarita Island Type) Gene - HIgR - HV1S - HVEC - Herpes Simplex Virus Type 1 Sensitivity Gene - Nectin Cell Adhesion Molecule 1 wt Allele - OFC7 - PRR - PRR1 - PVRL1 - PVRR - PVRR1 - Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) Gene - SK-12