5-Hydroxylysine

**Semantic type:** Amino Acid, Peptide, or Protein

**Definition:** A hydroxylated amino acid derivative of lysine that arises from post-translational modification. Lysine is converted into 5-hydroxylysine by lysyl hydroxylase, an oxoenzyme that catalyzes the hydroxylation of carbon-5 in lysyl residues found in proteins or peptides. Hydroxylysine residues are required for the formation and stability of triple helical collagen fibrils.

**Synonyms:** - (2S,5R)-2,6-Diamino-5-Hydroxyhexanoate - (2S,5R)-2,6-Diamino-5-Hydroxyhexanoic Acid - (2S,5R)-5-Hydroxylysine - 5-Hydroxy-Lysine - Alpha,Epsilon-Diamino-Delta-Hydroxycaproate - Alpha,Epsilon-Diamino-Delta-Hydroxycaproic Acid - Delta-Hydroxylysine - Erythro-5-Hydroxy-L-Lysine - HYDROXYLYSINE - Hydroxy-Lysine - Hydroxylysine - L-Delta-Hydroxylysine - L-Hydroxylysine