HMB-45

**Semantic type:** Amino Acid, Peptide, or Protein|Immunologic Factor|Indicator, Reagent, or Diagnostic Aid|Pharmacologic Substance

**Definition:** A mouse monoclonal antibody that is used in anatomic pathology as a marker for melanocytic tumors. This antibody recognizes melanocyte protein PMEL (PMEL17 or SILV).

**Synonyms:** - HMB45 - Human Melanoma Black 45 - Melanoma (gp100) Antibody (HMB45) - Monoclonal Mouse Anti-Human Melanocyte Protein PMEL - Monoclonal Mouse Anti-Human Melanosome, Clone HMB-45