CARD14 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human CARD14 wild-type allele is located in the vicinity of 17q25 and is approximately 39 kb in length. This allele, which encodes caspase recruitment domain-containing protein 14, is involved in the inhibition of apoptosis. Mutation of the gene is associated with both psoriasis type 2 and autosomal dominant pityriasis rubra pilaris.

**Synonyms:** - BIMP2 - CARMA2 - Caspase Recruitment Domain Family, Member 14 wt Allele - PRP - PSORS2 - PSS1 - Psoriasis Susceptibility 2 Gene