LZTS1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human LZTS1 wild-type allele is located in the vicinity of 8p22 and is approximately 58 kb in length. This allele, which encodes leucine zipper putative tumor suppressor 1 protein, is involved in cell cycle regulation, cell growth modulation, transcriptional regulation, and tumor suppression. Mutation of the gene is associated with esophageal squamous cell carcinoma and several other neoplastic diseases.

**Synonyms:** - F37 - FEZ1 - Leucine Zipper, Putative Tumor Suppressor 1 wt Allele