Muckle-Wells Syndrome

**Semantic type:** Disease or Syndrome

**Definition:** An autoinflammatory disease caused by mutations in the NLRP3 gene which encodes cryopyrin. It is characterized by recurrent episodes of urticaria and fever which develop in infancy. It may lead to sensorineural hearing loss and/or amyloidosis.

**Synonyms:** - MWS - MWS