RAB7A wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human RAB7A wild-type allele is located in the vicinity of 3q21 and is approximately 89 kb in length. This allele, which encodes ras-related protein Rab-7a, plays a role in the localization and function of both endosomes and lysosomes. Mutation of the gene is associated with Charcot-Marie-Tooth disease 2B.

**Synonyms:** - CMT2B - PRO2706 - RAB7 - RAB7, Member RAS Oncogene Family Gene - RAB7A, Member RAS Oncogene Family wt Allele