Circadian Locomoter Output Cycles Protein Kaput

**Semantic type:** Amino Acid, Peptide, or Protein|Enzyme

**Definition:** Circadian locomoter output cycles protein kaput (846 aa, ~95 kDa) is encoded by the human CLOCK gene. This protein plays a role in the modulation of histone acetylation that regulates both gene expression and circadian rhythms.

**Synonyms:** - CLOCK - Circadian Locomoter Output Cycles Kaput Protein - Class E Basic Helix-Loop-Helix Protein 8 - Clock Homolog - EC 2.3.1.48 - bHLHe8 - hCLOCK