ENAH Protein Isoform Expression Assay

**Semantic type:** Laboratory Procedure

**Definition:** A proprietary immunofluorescent assay that quantifies the relative expression levels of all isoforms of the actin regulatory protein, protein enabled homolog (Mena or ENAH), including Mena(INV) and Mena11a. Mena(INV) expression is elevated and Mena11a expression is diminished or absent in invasive tumor cells, which may have increased metastatic potential. Therefore, this assay may be able to predict a patient's risk for tumor metastasis.

**Synonyms:** - Mena Protein Isoform Expression Assay - MenaCalc - MenaCalc Platform - Protein Enabled Homolog Isoform Expression Assay