Circulating Clonotypic B-Cell

**Semantic type:** Cell

**Definition:** A B-lymphocyte that is hyperdiploid, has clonotypic IgH gene rearrangements, and is found in the peripheral blood of patients with monoclonal gammopathy of undetermined significance or multiple myeloma.

**Synonyms:** - CCBC - Circulating Clonotypic B Cell - Circulating Clonotypic B Lymphocyte - Circulating Clonotypic B-Lymphocyte