Pseudomyogenic Hemangioendothelioma

**Semantic type:** Neoplastic Process

**Definition:** An intermediate, rarely metastasizing blood vessel neoplasm that more frequently affects young adult males and usually arises in the lower limbs. In approximately half of the affected patients the tumor is painful and in two-thirds of the patients the tumor is multifocal. Morphologically it is characterized by the presence of sheets and fascicles of spindle cells with abundant eosinophilic cytoplasm and vesicular nuclei. Cytologic atypia is usually mild. Approximately 60% of the patients develop local recurrences or additional tumors in the same anatomic region.

**Synonyms:** - Epithelioid Sarcoma-Like Hemangioendothelioma - Pseudomyogenic (Epithelioid Sarcoma-Like) Hemangioendothelioma