Chondrosarcoma, Grade 3

**Semantic type:** Neoplastic Process

**Definition:** A high-grade chondrosarcoma arising in the medulla of bone or within the cartilaginous cap of a pre-existing osteochondroma. It is characterized by the presence of increased cellularity and a greater degree of nuclear atypia, hyperchromasia, and mitotic activity as compared to grade 2 chondrosarcoma.

**Synonyms:** - Grade III Chondrosarcoma - High Grade Chondrosarcoma - High-Grade Chondrosarcoma