Primary Bone Non-Hodgkin Lymphoma

**Semantic type:** Neoplastic Process

**Definition:** A non-Hodgkin lymphoma that arises from the bone, without lymph node or other extranodal involvement. The femur, spine, and pelvic bones are the most frequently affected areas. The majority of cases are diffuse large B-cell lymphomas. Most patients present with pain in the affected area. Systemic symptoms are rare.

**Synonyms:** - Primary Non-Hodgkin Lymphoma of Bone - Primary Non-Hodgkin Lymphoma of the Bone