PLA2G7 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human PLA2G7 wild-type allele is located within 6p21.2-p12 and is approximately 31 kb in length. This allele, which encodes platelet-activating factor acetylhydrolase protein, plays a role in the modulation of the inflammatory activity of platelet-activating factor. Mutation of the gene is associated with platelet-activating factor acetylhydrolase deficiency and increased susceptibility to asthma or atopy.

**Synonyms:** - LDL-PLA2 - LP-PLA2 - PAFAD - PAFAH - Phospholipase A2, Group VII (Platelet-Activating Factor Acetylhydrolase, Plasma) wt Allele - Platelet-Activating Factor Acetylhydrolase, Plasma Gene