5-Iodouracil

**Semantic type:** Organic Chemical

**Definition:** A halogenated pyrimidine analog containing an iodine atom linked to a pyrimidine ring. 5-Iodouracil (IU) gets incorporated into DNA. IU is a metabolite of idoxuridine (IUdR; 5-iododeoxyuridine) and the IUdR prodrug ropidoxuridine (IPdR).

**Synonyms:** - 2,4(1H,3H)-Pyrimidinedione, 5-Iodo- - 2,4(1H,3H)-Pyrimidinedione, 5-Iodo- - 2,4-Dihydroxy-5-iodopyrimidine - 5-IODOURACIL - IU - NSC 57848 - Uracil, 5-Iodo-