VEGF:VEGFR Complex

**Semantic type:** Amino Acid, Peptide, or Protein

**Definition:** A ligand-receptor complex comprised of a homodimer of vascular endothelial growth factor (VEGF) family proteins bound to a heterodimer of vascular endothelial growth factor receptor (VEGFR) family proteins. Ligand binding triggers receptor dimerization and cross-receptor tyrosine phosphorylation, which promotes downstream signal transduction.

**Synonyms:** - VEGF-VEGFR Complex - VEGF/VEGFR Complex - Vascular Endothelial Growth Factor-Vascular Endothelial Growth Factor Receptor Complex - Vascular Endothelial Growth Factor/Vascular Endothelial Growth Factor Receptor Complex - Vascular Endothelial Growth Factor:Vascular Endothelial Growth Factor Receptor Complex