Hyperlipoproteinemia, Type IIa

**Semantic type:** Disease or Syndrome

**Definition:** An autosomal dominant inherited disorder characterized by very high levels of low-density lipoprotein cholesterol (LDL-C) and total cholesterol in the blood. It is usually caused by mutations in the LDLR gene which is located on the short arm of chromosome 19.

**Synonyms:** - FH - Familial Hypercholesterolemia - Hyperlipidemia Type IIa - Type IIa Hyperlipidemia