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C123846Level 7

BCR/ABL1 Fusion Protein with ABL1 NP_005148.2:p.T315I

**Semantic type:** Amino Acid, Peptide, or Protein

**Definition:** A fusion protein encoded by the BCR/ABL1 fusion gene with ABL1 NM_005157.4:c.944C>T mutation. This protein is comprised of the N-terminus of the breakpoint cluster region protein fused to almost the entire tyrosine-protein kinase ABL1 protein where the threonine at position 315 of the ABL1 protein has been replaced by isoleucine.

**Synonyms:** - BCR-ABL T315I Mutation - BCR-ABL Thr315Ile Mutation - BCR-ABL1 T315I Mutation - BCR-ABL1 Thr315Ile Mutation - BCR/ABL Fusion Protein with T315I - BCR/ABL Fusion Protein with Thr315Ile - BCR/ABL T315I Mutation - BCR/ABL Thr315Ile Mutation - BCR/ABL1 Fusion Protein with ABL1 NP_005148.2:p.Thr315Ile - BCR/ABL1 Fusion Protein with NP_005148.2:p.T315I - BCR/ABL1 Fusion Protein with NP_005148.2:p.Thr315Ile - BCR/ABL1 T315I Mutation - BCR/ABL1 Thr315Ile Mutation - BCR::ABL1 Fusion Protein with ABL1 NP_005148.2:p.T315I - T315I - T315I Mutation

GET/api/v1/systems/nci_thesaurus/nodes/C123846
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