Protein Disulfide-Isomerase Family

**Semantic type:** Amino Acid, Peptide, or Protein|Enzyme

**Definition:** A family of isomerase enzymes that reside in the endoplasmic reticulum and act as chaperones during protein folding. They catalyze the rearrangement of disulfide bonds between cysteine residues within proteins as they undergo the folding step of protein maturation.

**Synonyms:** - EC 5.3.4.1 - PDI - PDI Family - Protein Disulfide Isomerase - Protein Disulfide Isomerase Family - Protein Disulfide-Isomerase