VCP wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human VCP wild-type allele is located in the vicinity of 9p13.3 and is approximately 17 kb in length. This allele, which encodes transitional endoplasmic reticulum ATPase protein, plays a role in maintenance of both the transitional endoplasmic reticulum and the Golgi apparatus. Mutation of the gene is associated with amyotrophic lateral sclerosis 14 and inclusion body myopathy with early-onset Paget disease and frontotemporal dementia 1 (IBMPFD1).

**Synonyms:** - ALS14 - CDC48, Yeast, Homolog of Gene - IBMPFD - TERA - Valosin Containing Protein wt Allele - Yeast Cdc48p Homolog Gene - p97