SETX wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human SETX wild-type allele is located in the vicinity of 9q34.13 and is approximately 95 kb in length. This allele, which encodes probable helicase senataxin protein, plays a role in the metabolism of both DNA and RNA. Mutation of the gene is associated with juvenile amyotrophic lateral sclerosis 4 and autosomal recessive spinocerebellar ataxia 1.

**Synonyms:** - ALS4 - AOA2 - Amyotrophic Lateral Sclerosis 4 Gene - KIAA0625 - SCAR1 - Senataxin wt Allele - Spinocerebellar Ataxia, Recessive, Non-Friedreich Type 1 Gene - bA479K20.2