PRKG1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human PRKG1 wild-type allele is located in the vicinity of 10q11.2 and is approximately 1307 kb in length. This allele, which encodes cGMP-dependent protein kinase 1 protein, plays a role in both protein phosphorylation and nitric oxide signaling. Mutation of the gene is associated with familial thoracic aortic aneurysm type 8.

**Synonyms:** - AAT8 - PGK - PKG - PRKG1B - PRKGR1B - Protein Kinase, cGMP-Dependent, Regulatory, Type I Gene - Protein Kinase, cGMP-Dependent, Regulatory, Type I, Alpha Gene - Protein Kinase, cGMP-Dependent, Regulatory, Type I, Beta Gene - Protein Kinase, cGMP-Dependent, Type I wt Allele - cGK - cGK 1 - cGK1 - cGKI - cGKI-Alpha - cGKI-BETA - cGMP-Dependent Protein Kinase, Type I, Alpha Gene - cGMP-Dependent Protein Kinase, Type I, Beta Gene