Dendritic Cell-Precision Multiple Antigen T-Lymphocytes

**Semantic type:** Cell|Pharmacologic Substance

**Definition:** A preparation of dendritic cell-precision multiple antigen T-cells (DC-PMAT) that have been induced to specifically target multiple undisclosed tumor-associated antigens (TAAs), with potential antitumor activity. Although the exact mechanism(s) of action through which DC-PMAT cells exert their effects has yet to be elucidated, upon infusion, these cells may stimulate the host immune system to mount a highly-specific cytotoxic T-lymphocyte (CTL) response against tumors expressing common TAAs, which leads to tumor cell lysis.

**Synonyms:** - DC-PMAT - Dendritic Cell-Precision Multiple Antigen T-Cells