Striatonigral Degeneration

**Semantic type:** Disease or Syndrome

**Definition:** A progressive neurodegenerative disorder caused by a disruption in the connection between the striatum and the substantia nigra. It is a type of multiple system atrophy (MSA). Signs and symptoms include rigidity, instability, impaired speech, and slow movements.

**Synonyms:** - Striatonigral degeneration