Chimeric Antigen Receptor

**Semantic type:** Receptor

**Definition:** A cell-surface receptor that has been engineered to combine novel features and specificities from various sources in order to enhance its antigen specificity. Engineered T-cells or B-cells will produce the specialized receptor that will be capable of binding to an epitope on its target cell.

**Synonyms:** - Artificial Antigen Receptor - CAR - Non-Native Antigen Receptor