CD42 Complex

**Semantic type:** Amino Acid, Peptide, or Protein

**Definition:** A heterotetrameric protein complex expressed on the surface of platelets that is involved in promoting platelet adhesion to von Willebrand factor during wound healing. This non-covalent complex is comprised of glycoprotein 5 (GPV; CD42d), glycoprotein 9 (GPIX; CD42a), and glycoprotein Ib (GPIb). GPIb is a heterodimer comprised of platelet glycoprotein Ib alpha chain (GPIba; CD42b) covalently bound to platelet glycoprotein Ib beta chain (GPIbb; CD42c).

**Synonyms:** - CD42 - CD42 Antigen - CD42a-d Complex - GPIb-V-IX - GPIb/V/IX - Glycoprotein Ib-V-IX - Glycoprotein Ib/V/IX Complex - Platelet Glycoprotein Ib-V-IX - Platelet Glycoprotein Ib/V/IX Complex