T-Cell Immunoreceptor with Ig and ITIM Domains

**Semantic type:** Amino Acid, Peptide, or Protein

**Definition:** T-cell immunoreceptor with Ig and ITIM domains (244 aa, ~26 kDa) is encoded by the human TIGIT gene. This protein is involved in immunomodulation and cell-cell adhesion.

**Synonyms:** - T-Cell Immunoreceptor with Immunoglobulin and ITIM Domains - TIGIT - V-Set and Immunoglobulin Domain-Containing Protein 9 - V-Set and Transmembrane Domain-Containing Protein 3