Activating PI3K Gene Mutation

**Semantic type:** Cell or Molecular Dysfunction

**Definition:** A change in the nucleotide sequence of any one of the genes encoding proteins in the phosphatidylinositol 3-kinase (PI3K) family that results in constitutive PI3K activity and aberrant activation of PI3K-dependent signaling pathways.

**Synonyms:** - Activating 1-Phosphatidylinositol 3-Kinase Gene Mutation - Activating PI3 Kinase Gene Mutation - Activating PI3-Kinase Gene Mutation - Activating PI3K Family Gene Mutation - Activating PI3K Mutation - Activating PI3K Mutation - Activating PIK3 Gene Mutation - Activating Phosphatidylinositide 3-Kinase Gene Mutation - Activating Phosphatidylinositol 3 Kinase Gene Mutation - Activating Phosphatidylinositol 3-Kinase Gene Mutation - Activating Phosphatidylinositol-3-Kinase Gene Mutation - Activating Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Gene Mutation