STAT3 Deficiency

**Semantic type:** Disease or Syndrome

**Definition:** A condition of decreased or absent presence or activity of signal transducer and activator of transcription 3 protein. Deficiency of this protein is associated with hyper-IgE syndrome.

**Synonyms:** - Autosomal dominant hyper-IgE syndrome - Hyper-IgE Recurrent Infection Syndrome - Job Syndrome - Job's syndrome - STAT3 deficiency