DOCK8 Deficiency

**Semantic type:** Disease or Syndrome

**Definition:** A condition of decreased or absent presence or activity of dedicator of cytokinesis protein 8. Deficiency of this protein is associated with autosomal recessive hyper-IgE recurrent infection syndrome.

**Synonyms:** - Autosomal Recessive hyper IgE syndrome - DOCK8 deficiency - Dedicator of Cytokinesis 8 Deficiency